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The Biopsy (Small Specimen) service at Medall provides expert histopathological examination of small tissue specimens — includi...
Also known as: Histopathology Biopsy · Small Specimen Biopsy · Tissue Biopsy Report · Histology Report · Microwave-Assisted Tissue Processing
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*Inclusive of home collection charges
The Biopsy (Small Specimen) service at Medall provides expert histopathological examination of small tissue specimens — including needle core biopsies, punch biopsies, shave biopsies, excisional biopsies, curettage specimens, and small surgical specimens — using the rapid Microwave-Assisted Tissue Processing technique. This method reduces tissue processing time from the traditional 12–24 hours to 2–4 hours while maintaining histological quality, enabling significantly faster diagnostic reporting. All specimens are examined and reported by Medall's qualified pathologists. Not a patient-ordered test — specimens are submitted by treating physicians, surgeons, or dermatologists.
Key benefits of this package include:
What Does the Biopsy — Small Specimen (Microwave Technique) Measure?
| Level / Result | Possible Interpretation |
|---|---|
| Benign / Normal histology | No malignancy or significant pathology — correlate with clinical picture; may require follow-up if symptoms persist |
| Inflammatory pattern (acute/chronic/granulomatous) | Inflammatory condition — specific pattern guides aetiology (e.g., granulomas suggest TB, sarcoidosis, Crohn's) |
| Dysplasia / Pre-malignant changes | Cellular abnormalities indicating cancer risk — grading (mild/moderate/severe) guides management (surveillance vs. treatment) |
| Malignant — invasive carcinoma | Cancer confirmed — full staging, multidisciplinary team review, and treatment planning required urgently |
| Malignant — in-situ carcinoma | Early cancer limited to epithelium without invasion — definitive treatment before progression to invasive cancer |
| Inconclusive / Insufficient material | Specimen inadequate for diagnosis — repeat biopsy with adequate material required |
Important Note: Histopathology reports are complex clinical documents — they must be reviewed and explained by the treating physician in the context of the patient's full clinical picture. A malignant biopsy result should never be communicated to a patient without appropriate medical consultation and counselling support. Special stains, immunohistochemistry (IHC), and molecular testing (FISH, PCR) may be required for complete tumour characterisation — your Medall pathologist will request these where appropriate.
Immunohistochemistry (IHC) — Beyond H&E Diagnosis: Modern histopathology extends beyond basic H&E staining to include Immunohistochemistry (IHC) — using specific antibodies to detect protein expression in tissue sections. IHC is essential for: tumour classification (e.g., ER/PR/HER2 in breast cancer determining hormonal therapy eligibility), tumour origin determination (CK7/CK20 patterns identify the primary site of metastatic carcinoma), lymphoma subtyping (CD20, CD3, CD10 etc.), sarcoma classification, and biomarker testing (PDL1 for checkpoint inhibitor eligibility, MLH1/MSH2/MSH6/PMS2 for Lynch syndrome). Medall's NABL-accredited histopathology laboratory offers a comprehensive IHC panel for complete tumour characterisation.
Book once, we handle the rest. Our certified phlebotomist arrives at your doorstep — your report is delivered within 24 hours.
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