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The Dengue Antigen (NS1) test detects the NS1 (Non-Structural Protein 1) of the dengue virus directly in blood — providing a highly accurate diagnosis of dengue fever in the earliest phase of infection (Days 1–5 of fever), before the immune system has generated detectable IgM antibodies. NS1 is secreted by all four dengue virus serotypes at high concentrations during the early viraemic phase, making it the preferred first-line test for acute dengue diagnosis. No fasting required.
Key benefits of this package include:
What Does the Dengue Antigen (NS1) Test Measure?
| Level / Result | Possible Interpretation |
|---|---|
| NS1 Negative (Days 1–5) | Dengue NS1 not detected — does not exclude dengue; false negatives possible (~10–20% of cases); add dengue IgM/IgG serology; clinical assessment essential |
| NS1 Positive (Days 1–5) | Active dengue virus infection confirmed — initiate dengue management protocol; daily platelet monitoring; watch for warning signs |
| NS1 Negative (After Day 5) | NS1 falls after Day 5 — test dengue IgM antibody which becomes detectable from Day 4–7; NS1 has reduced utility after Day 5 |
| NS1 Positive + Platelet < 100,000/µL | Dengue with thrombocytopenia — increased severity risk; close monitoring and possible hospitalisation |
| NS1 Positive + Warning signs (severe abdominal pain, persistent vomiting, bleeding) | Severe dengue — immediate hospitalisation required; dengue haemorrhagic fever or dengue shock syndrome evaluation |
Important Note: A negative NS1 result does not exclude dengue — particularly after Day 5 or in secondary dengue infection (where rapid antibody response may clear NS1 faster). The complete dengue panel (NS1 antigen + IgM + IgG antibodies) provides the highest sensitivity across all stages of the disease. All dengue-suspected patients require clinical assessment, platelet monitoring, and haematocrit monitoring regardless of NS1 result.
Dengue Warning Signs — When to Seek Emergency Care: Most dengue infections are self-limiting and managed at home with oral fluids and paracetamol. However, approximately 5% of cases progress to severe dengue — a life-threatening condition requiring hospitalisation. Warning signs that require immediate emergency evaluation: severe abdominal pain or tenderness, persistent vomiting, clinical fluid accumulation (pleural effusion, ascites), mucosal bleeding (gum bleeding, haemoptysis, blood in urine or stool), lethargy or restlessness, liver enlargement > 2 cm, and rising haematocrit with rapid platelet decline. Any patient with dengue and warning signs should not wait for platelet counts — proceed to emergency evaluation immediately.

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Trusted by millions of Customers across South India — these are the tests our doctors recommend most.